ICGC Goals, Structure, Policies & Guidelines April 2008

ICGC Goals, Structure, Policies & Guidelines April 2008: PDF

D. Structure of the Consortium

Section D – Structure of the Consortium PDF


E.1  Informed Consent, Access and Ethical Oversight

Section E.1 – Informed Consent, Access and Ethical Oversight PDF


E.3  Publication Policy

Section E.3 – Publication Policy PDF


E.6 Quality Standards of Samples

Section E.6 – Quality Standards of Samples PDF


E.7 Study Design and Statistical Issues

Section E.7 – Study Design and Statistical Issues PDF


Updates to Goals, Structure, Policies & Guidelines

ICGC Funding Members Launching Large-Scale Projects (more than 500 samples)

April 2008 March 2010 May 2012, Current

1) Single funding agency; or
2) Alliance of organizations, with a representative from a single organization within the coalition appointed to the EXEC. (See Structure, below)

To support the characterization of 500 unique cases of one cancer type or subtype to the degree of comprehensiveness described in this document, ICGC Funding Members will be required to provide the equivalent of a minimum of $10 million USD in total on such a project, distributed over 5 years, for operations (salaries, consumables, etc.), excluding overhead/indirect costs and equipment. It is recognized that some countries may have lower research costs, or may be able to provide material contributions (such as specimens) that may offset the level of commitment. Guidelines will be developed to evaluate the value of “in-kind” or lower contributions, with a general principle that the Responsibility will rest with the funding organization to ensure that the level of support will be sufficient to mount a cancer genome project that will meet the guidelines of the ICGC.

Funding agencies supporting large-scale projects can self-nominate to the ICGC Executive Committee (described below) which has the responsibility for review and approval of nominations. Funding agencies are encouraged to apply for Funding Member status as they become ready to contribute to the ICGC and adopt the Consortium’s policies and guidelines.